WebPSGL1 hi Ly6C lo compartment consists of fully differentiated Tfh and Th1 cells. (A–D) LCMV-specific Blimp1-YFP SM (CD45.1 + ) CD4 T cells were divided into three … WebP-selectin glycoprotein ligand-1 (PSGL-1) has long been studied as an adhesion molecule involved in immune cell trafficking and is recognized as a regulator of many facets of immune responses by myeloid cells. PSGL-1 also regulates T cell migration during homeostasis and inflammatory settings. However, recent findings indicate that PSGL-1 …
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WebSep 6, 2016 · Terminally differentiated Th1 CD4 T cells express PSGL1 + and Ly6C + during acute LCMV infection, and these markers enrich for TBET and granzyme B expression ( 28 ). However, during chronic infection Ly6C + effector cells are lost and T FH predominate as a CD4 T cell subset ( 25, 29 ). WebLY6C Hi monocytes in mice express L-selectin, P-selectin glycoprotein ligand 1 (PSGL1), lymphocyte function-associated antigen 1 (LFA1, also known as α L β 2 integrin), macrophage receptor 1 (MAC1, also known as integrin α M β 2 ), platelet endothelial cell adhesion molecule (PECAM1), and very late antigen 4 (VLA4, also known as integrin α 4 β … futures trading indicators
Differential expression of Ly6C and T-bet distinguish effector and ...
WebAnalyses of PSGL1 and Ly6c expression on dKO cells found little or no PSGL1lo Ly6c– (Tfh) cells and a preponderance of PSGL1+ Ly6clo cells, which, in WT mice, are enriched in memory pre-cursors (Marshall et al., 2011; Fig. S1, B and C). Distinct mechanisms underpin Bcl6 requirements for Tfh and T cmp differentiation Web小鼠中的ly6c hi 单核细胞表达l-选择素、p-选择素糖蛋白配体1(psgl1)、淋巴细胞功能相关抗原1(lfa1,也称为α l β 2 整合素)、巨噬细胞受体1(mac1,也称为整合素α m β 2 )、血小板内皮细胞黏附分子(pecam1)和迟现抗原4(vla4,也称为整合素α 4 β 1 ),所有 ... WebThe Seekers - Massachusetts (2002) gko knowledge online