Phospho eif2a
WebHuman Phospho-eIF2 alpha (S52) Antibody Summary Species Reactivity Human Specificity Detects human Phospho-eIF2 alpha (S52) in ELISAs and Western blots. Source Monoclonal Rat IgG 2B Clone # 849159 Purification Protein A or G purified from hybridoma culture supernatant Immunogen Phosphopeptide containing the human eIF2 alpha S52 site WebRayBio® Phospho-eIF-2A (S52) and Total eIF-2A ELISA kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in human cell lysates. By determining phosphorylated eIF-2A protein in your experimental model system, you can verify pathway activation in your cell lysates.
Phospho eif2a
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WebExtensive phosphorylation of eIF2 alpha and strong inhibition of eIF2B activity can result in the downregulation of the overall rate of protein synthesis; less marked changes may lead … WebThe PathScan ® Phospho-eIF2α (Ser51) Sandwich ELISA Kit #7286 detects endogenous levels of eIF2α protein when phosphorylated at Ser51 as shown in Figure 1. Kit sensitivity is shown in Figure 2. This kit detects proteins from the indicated species, as determined through in-house testing, but may also detect homologous proteins from other species.
WebNov 26, 2024 · Phospho-eIF2α has increased affinity to the eIF2β subunit and prevents the regeneration of guanosine triphosphate (GTP) in the ternary complex eIF2-GTP- Met … WebFeb 26, 2015 · Phospho-eIF2α resistance has been observed both in yeast and in mammalian cells. In yeast, mutations in eIF2B (the GEF for eIF2) and eIF5 (the 48S PIC …
WebPhosphorylation of the eukaryotic initiation factor 2 (eIF2) α subunit is a well-documented mechanism to downregulate protein synthesis under a variety of stress conditions. eIF2 binds GTP and Met-tRNAi and transfers Met-tRNA to the 40S subunit to form the 43S preinitiation complex (1,2). eIF2 promotes a new round of translation initiation by … WebEIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of …
WebEIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of …
WebThe ratio of phospho-eIF2α to total eIF2α was determined by scanning densitometry and image analysis (Image J, NCBI). ... It is possible that queuine reduces the phosphorylation level of eIF2a ... inbound freight handlerWebJul 16, 2024 · eIF2α Antibody (D-3) is an IgG 1 κ mouse monoclonal eIF2 alpha antibody (also designated EIF2A antibody, eIF2 alpha antibody, or EIF2S1 antibody) that detects the eIF2 alpha protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. eIF2α Antibody (D-3) is available as both the non-conjugated anti-eIF2 alpha antibody form, as … inbound freight cost of goods soldWebOur eIF2A polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the eIF2A antibody that fits your needs. Choose from 1 of 14 eIF2A antibodies, which have been validated in experiments with 25 publications and 60 images featured in our data gallery. inbound freight chargesWebHuman Phospho-eIF2 alpha (S52) Antibody Summary. Detects human Phospho-eIF2 alpha (S52) in ELISAs and Western blots. Lyophilized from a 0.2 μm filtered solution in PBS with … inbound freight costWebPhospho-eIF2alpha (Ser51) Antibody detects endogenous eIF2alpha only when phosphorylated at Ser51. The antibody does not recognize … inbound freight accountingWebJun 19, 2024 · EIF2α phosphorylation: a hallmark of both autophagy and immunogenic cell death EIF2α phosphorylation: a hallmark of both autophagy and immunogenic cell death Mol Cell Oncol. 2024 Jun 19;7 (5):1776570. doi: 10.1080/23723556.2024.1776570. eCollection 2024. Authors Juliette Humeau 1 2 , Lucillia Bezu 1 2 3 , Oliver Kepp 1 2 , Guido Kroemer 1 … inbound freight meaningWebMay 13, 2024 · Other Gcn − mutants in eIF2Bδ (E377K and L381Q) disrupt both yeast and mammalian eIF2 phospho-regulation despite allowing efficient phosphorylation of Ser52 9,27. Here, δE377 and δL381 are ... inbound freight taxable